Cemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally Advanced MSI-H Colorectal Cancer

Recruiting now · Phase 2

Conditions studied: Colorectal Cancer

In brief

The purpose of this study is to evaluate the safety and clinical activity of cemiplimab and the combination of cemiplimab/fianlimab in microsatellite unstable localized or locally advanced colorectal cancer diagnosed in patients age 70 or greater or in patients age 18 or greater considered poor candidates for surgery or unwilling to undergo surgery.

Key facts

Study ID
NCT06205836
Run by
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
People needed
44
Starts
2024-06-13
Expected to finish
2030-05-01
Last updated by the study team
2026-05-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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