Interest of Intensive Postoperative Rehabilitation Following Minimally Invasive Lung Resection

Recruiting now · Not applicable

Conditions studied: Lung Cancer

In brief

For patients diagnosed with non-small cell lung cancer (NSCLC), lung resection surgery remains the gold standard for curative treatment. This scheduled operation is associated with significant morbidity, particularly in individuals with impaired cardio-respiratory function. Therefore, patient optimization is paramount. The process begins prior to surgery with preoperative rehabilitation, commonly referred to as "prehabilitation," serving as the foundation for various Enhanced Recovery After Surgery programs. The training methods employed in these programs bear similarity to rehabilitation programs designed for patients with chronic obstructive pulmonary disease (COPD). Postoperatively, patients undergoing thoracic surgery partake in daily physiotherapy sessions, aiming to optimize the postoperative period, minimize the respiratory impact of surgery, and reduce the length of hospital stay. However, this treatment is not currently standardized and primarily involves early mobilization, including walking, and respiratory physiotherapy. Our focus is on the intensity and methods of this postoperative rehabilitation. There is limited literature on effective early rehabilitation in the immediate postoperative period, and existing studies suggest no adverse events associated with postoperative training. Therefore, our objective is to assess whether combining endurance training with standard physiotherapy (walking and respiratory physiotherapy) enhances the functional capacity of individuals undergoing lung surgery.

Key facts

Study ID: NCT06202222
Run by: University Hospital, Rouen
People needed: 184
Starts: 2024-09-09
Expected to finish: 2027-05-09
Last updated by the study team: 2025-09-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Patients requiring surgery for diagnosed or undergoing diagnosis of lung cancer.
Patients in need of major lung resection through a minimally invasive approach.
Patients capable of performing the chair rise test.

You may not qualify if…

Contraindications to cyclo-ergometry: Deep vein thrombosis in a lower limb. Patients with one or both lower limbs amputated. Rheumatological pathology, trauma, or previous surgery in the lower limb, pelvis, or spine, resulting in limited joint amplitude or strict immobilization.
Dermatological conditions with severe lesions preventing prolonged sitting on a bicycle.
Glasgow score less than 15.
Patients who have not undergone pulmonary resection by minimally invasive surgery.
Patients hospitalized outside the thoracic surgery department before the first post-operative visit with the physiotherapist on Day 0.

Where it is running

Valenciennes, Hospital — Valenciennes, Hauts-de-France, France (enrolling)
CAEN, university Hospital — Caen, Normandy, France (enrolling)
Rouen, University Hospital — Rouen, Normandy, France (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.