Low-intensity Physical-cognitive Exercise and Cognitive Function

Recruiting now · Not applicable

Conditions studied: Mild Cognitive Impairment

In brief

This study aims to examine the effects of low-intensity, combined physical-cognitive exercise on cognitive function of older people with mild cognitive impairment (MCI) and identify the mechanisms by which this exercise protocol exerts cognitive function. Older adults with MCI will be recruited to either an exercise or a control group. Low-intensity, combined physical-cognitive exercise will be prescribed to the exercise group 3 times per week for 3 months while the control group will maintain their routine lifestyle. It is hypothesized that at the end of the trial, participants in the exercise group will demonstrate significant improvement in cognitive performance and circulating biomarkers compared to baseline and the control group.

Key facts

Study ID

NCT06201533

Run by

Chiang Mai University

People needed

64

Starts

2024-04-07

Expected to finish

2026-03-01

Last updated by the study team

2026-02-19

Who can join

Age: 60 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• meeting the criteria for MCI (or mNCD) based on the recent DSM-V criteria
• comprehend instructions and able to comply with the study procedures
• not taking any medications for their cognition and not planning to start medications during the study trial

You may not qualify if…

• presence of medical condition(s) unsafe to exercise or affect cognition and mobility
• presence of depressive symptoms
• exercise regularly

Where it is running

• Department of Physical Therapy, Faculty of Associated Medical Sciences, Chiang Mai University — Chiang Mai, Thailand (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.