MRD-guided Prognosis Prediction and Adjuvant Treatment Based on CTC and ctDNA in NSCLC
Recruiting now
Conditions studied: Non-small Cell Lung Cancer
In brief
This is a prospective cohort study, which aims to evaluate the effectiveness and superiority of a novel minimal residual disease-guided prognosis monitoring and adjuvant treatment in stage IIA-IIIC non-small cell lung cancer.
Key facts
- Study ID
- NCT06198868
- Run by
- Jiangsu Cancer Institute & Hospital
- People needed
- 60
- Starts
- 2024-02-01
- Expected to finish
- 2027-02-01
- Last updated by the study team
- 2024-01-12
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Written informed consent must be signed before implementing any enrollment-related procedures;
- Age ≥18 years old;
- Patients with histologically or cytologically confirmed stage IIA-IIIC NSCLC (International Association for the Study of Lung Cancer and American Joint Committee on Classification of Cancer, 8th Edition TNM staging)；
- There is no special restriction on the source of genetic test report.
- According to the Response Evaluation Criteria in Solid Tumors (RECIST, version 1.1), there is at least one radiographically measurable lesion.
- Have not received any previous systemic antitumor therapy for advanced diseases.
- No serious abnormalities of hematopoietic function, heart, lung, liver, kidney function and immune system.
- ECOG score: 0-1;
- Expected survival time > 3 months.
You may not qualify if…
- Received surgical treatment for lung tumors.
- Received neoadjuvant chemotherapy or radiotherapy.
- Received cellular therapy within the last 1 year.
- Treated but uncontrolled diabetes, mellitus, asthma, autoimmune diseases and other chronic diseases.
- Participated in other clinical trials (including research vaccines, drugs, medical devices, etc.) within one month.
Where it is running
- Jiangsu Cancer Institute & Hospital — Nanjing, Jiangsu, China (enrolling)
Full record on ClinicalTrials.gov
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