Feasibility, Safety and Acceptability of a Mobile Health Delivered Exercise Training Program in Patients With Nonalcoholic Steatohepatitis
Completed · Not applicable
Conditions studied: NASH - Nonalcoholic Steatohepatitis, NASH, Exercise, Liver
In brief
This study will be a pilot study to evaluate the feasibility, safety and acceptability of Exercise and Liver FITness (EL-FIT), a mHealth exercise training program previously validated in patients with cirrhosis in patients with nonalcoholic steatohepatitis.
Key facts
- Study ID
- NCT06195943
- Run by
- Milton S. Hershey Medical Center
- People needed
- 17
- Starts
- 2024-02-01
- Expected to finish
- 2026-03-01
- Last updated by the study team
- 2026-04-08
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adults age >18 years
- Evidence of NASH indicated by at least one of the following
- Liver biopsy with evidence of steatohepatitis (NAS >=4) within 6 months of the screening interval or;
- Historical Imaging study (e.g., ultrasound, CT, MRI) with hepatic steatosis and one of the following non-invasive tests within 6 months of the screening interval: i. FIB-4 >= 1.3 or; ii. NFS >= -1.44 or; iii. ELF >= 7.7 or; iv. VCTE kPa >=8 or; v. ARFI >=1.3 or; vi. FAST >= 0.35 or; vii. MRE kPa >=2.55 or; viii. MAST > 0.165 or;
- Possession of a smartphone
You may not qualify if…
- Active cardiac symptoms precluding participation in vigorous exercise
- Active or recent participation in exercise training program within the last 90 days
- Active or recent weight-loss supplement use within the last 90 days (does not include GLP-1 receptor agonist use)
- Active illicit substance use
- Cancer that is active
- Cirrhosis
- Exercise identified to be unsafe by study PI or EL-FIT mHealth program
- Inability to provide informed consent
- Inability to walk > 2 blocks
- Institutionalized/prisoner
- Other chronic liver disease (e.g., viral hepatitis)
Where it is running
- Penn State Hershey Medical Center — Hershey, Pennsylvania, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.