Contrast Echocardiography During Exercise to Assess Pulmonary Blood Volume
Recruiting now
Conditions studied: Heart Failure, Pulmonary Vascular Disease
In brief
The purpose of this study is to evaluate whether pulmonary blood volume (PBV) derived from contrast echocardiography can serve as a non-invasive surrogate for invasive pulmonary artery wedge pressure (PAWP) during exercise. Also, to compare changes in PBV with exercise in patients with and without heart failure and pulmonary vascular disease.
Key facts
- Study ID
- NCT06195059
- Run by
- Mayo Clinic
- People needed
- 800
- Starts
- 2024-07-30
- Expected to finish
- 2026-11-01
- Last updated by the study team
- 2025-08-14
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients referred to the cardiac catheterization laboratory for invasive exercise right heart catheterization for evaluating exertional dyspnea. Investigators will include patients with normal or low EF, and across the spectrum of pulmonary hypertension severity.
You may not qualify if…
- Patient inability or unwillingness to undergo echocardiography including a contrast method, or if echocardiography would, in the opinion of the investigator, somehow compromise the quality of data acquisition for the clinical case.
- Prior adverse reaction to echo contrast administration
Where it is running
- Mayo Clinic in Rochester — Rochester, Minnesota, United States (enrolling)
Full record on ClinicalTrials.gov
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