Risk and Resilience to Suicide Following Late-Life Spousal Bereavement

Recruiting now · Not applicable

Conditions studied: Suicide, Bereavement

In brief

The purpose of the RISE study is to examine how the 24-hour rhythm of sleep and social activity relate to mood and suicidal ideation among older adults that recently lost a spouse or life partner.

Key facts

Study ID

NCT06191484

Run by

University of Pittsburgh

People needed

169

Starts

2023-11-20

Expected to finish

2029-12-01

Last updated by the study team

2025-11-12

Who can join

Age: 65 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Bereaved < or = to 12 months from spousal/partner loss
• > or = to 65 years old
• Verified history of suicide attempt/attempts and/or current or past history of Major Depressive Disorder/Major Depressive Episode (MDD/MDE) (without psychotic features), or history of depression severe enough to trigger treatment, or current subsyndromal depression (> or = to 9 HDRS)
• No diagnosis of schizophrenia/schizoaffective disorders/bipolar/current psychosis
• Does not reside in nursing home
• Not a current shift worker
• No major cognitive impairment: TICS score of > or = to 27

You may not qualify if…

• Bereaved >12 months from spousal/partner bereavement
• < 65 years old
• Patient is not spousal/partner bereaved (ex: parent, sibling, etc.)
• Prior diagnosis of schizophrenia/schizoaffective disorders/bipolar/current psychosis or medications listed indicate diagnosis of these disorders/MDD or MDE with psychotic features
• Major cognitive impairment: TICS score of <27
• Current shift worker
• Resides in a nursing home
• Unstable medical condition (e.g., unstable angina, end stage renal disease)

Where it is running

• University of Pittsburgh (UPMC) — Pittsburgh, Pennsylvania, United States (enrolling)

Full record on ClinicalTrials.gov

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