BrighT STAR LIBRA: Leveraging Implementation Science for Blood Culture Reduction Approaches

Running, not enrolling · Not applicable

Conditions studied: Blood Culture Rates, Antibiotic Stewardship, Implementation Science

In brief

This study will compare two strategies that target distinct determinants of blood culture overuse in an exploratory, hybrid, pilot trial in 8 PICUs. It aims to determine if there is any association between specific strategies used to reduce blood culture overuse on unit-wide blood culture rates, patient safety, and concurrently explore aspects of the implementation process (acceptability, feasibility, appropriateness).

Key facts

Study ID

NCT06187662

Run by

Children's Hospital of Philadelphia

People needed

8

Starts

2023-01-01

Expected to finish

2027-04-01

Last updated by the study team

2025-10-31

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Males or females over 18 years old
• PICU clinicians with direct patient care roles

You may not qualify if…

• Non-English speaking
• PICU clinicians who report to the investigator

Where it is running

• UCLA Mattel Children's Hospital — Los Angeles, California, United States
• UCSF Benioff Children's Hospital Mission Bay — San Francisco, California, United States
• Nemours / AI DuPont Hospital for Children — Wilmington, Delaware, United States
• Riley Hospital for Children — Indianapolis, Indiana, United States
• Norton Children's Hospital — Louisville, Kentucky, United States
• Kravis Children's Hospital — New York, New York, United States
• New York-Presbyterian Morgan Stanley Children's Hospital — New York, New York, United States
• Children's Hospital of Wisconsin — Milwaukee, Wisconsin, United States

Full record on ClinicalTrials.gov

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