Effects of Including a Chronic Pain Neuroscience Education Program for Individuals With Knee OA
Recruiting now · Not applicable
Conditions studied: Osteoarthritis, Knee
In brief
Research participants diagnosed with knee osteoarthritis will be randomized through a draw using sealed opaque envelopes indicating two groups: 1. therapeutic exercises, 2. therapeutic exercises + chronic pain neuroscience education program. The primary outcome will be functional performance using a patient-reported measure, the Knee Injury and Osteoarthritis Outcome Score (KOOS). The selected secondary outcomes will be pain intensity by the numerical pain scale (END), physical function reported by the patient by the patient-specific functional scale (EFEP), Pain self-efficacy questionnaire (PSEQ), functional mobility by the timed up and test (TUG), general effect perceived through the global perception scale (EPG), muscle strength through Maximum Voluntary Isometric Contraction (MVIC) and functionality and disability through the World Health Organization Disability Assessment Schedule (WHODAS).
Key facts
- Study ID
- NCT06187038
- Run by
- University of Nove de Julho
- People needed
- 92
- Starts
- 2024-05-28
- Expected to finish
- 2026-12-15
- Last updated by the study team
- 2026-05-22
Who can join
Age: 40 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- A clinical diagnosis of knee osteoarthritis (knee pain for > 3 months
- Morning stiffness <30 minutes
- Crepitus
- Bone tenderness, and absence of palpable heat and/or diagnosis established radiographically (determined by Kellgren and Lawrence grade 1 to 3 on a scale 1 up to 4)
You may not qualify if…
- Hip OA
- severe osteoporosis
- Fibromyalgia
- Medical history of tumors or cancer
- Active inflammatory joint diseases (rheumatoid arthritis, gout)
- Undergoing any lower extremity joint replacement
- Neurological diseases (Parkinson's disease, stroke, Multiple Sclerosis, muscular dystrophy, motor neuron disease, Alzheimer's disease, cognitive and cardiopulmonary impairment that may prevent or limit the performance of exercises, use of a gait assistance device, history of recent knee trauma.
- Having undergone any form of treatment involving physiotherapy, intra-articular corticosteroids, anti-inflammatories or chondroprotective in the last six months
Where it is running
- Nove de Julho University — São Paulo, Brazil (enrolling)
Full record on ClinicalTrials.gov
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