Resistance Training to Individuals for Cognitive Impairment With Dementia

Recruiting now · Not applicable

Conditions studied: Mild Cognitive Impairment, Mild Dementia

In brief

This research project aims to analyze the effects of different resistance training volumes on cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment. First the investigators will analyze the effects of a single resistance training session (acute effects) with one and three sets on hemodynamic and physical performance in individuals with mild cognitive impairment. After, the investigators will analyze the effects of an 8-week resistance training program with one or three sets on cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment. The investigators hypothesize that a single resistance training session of one or three sets will increase the acute hemodynamic and physical performance stress in individuals with mild cognitive impairment, although with a higher magnitude in the session with three sets. Furthermore, we hypothesize that eight weeks of resistance training with one or three sets will induce similar improvements in cognitive function, oxidative stress, immunological response, lipid profile, glycemic status, liver function, muscle function, hemodynamic response, and physical performance in individuals with mild cognitive impairment.

Key facts

Study ID

NCT06185010

Run by

University of Beira Interior

People needed

80

Starts

2023-12-01

Expected to finish

2024-12-31

Last updated by the study team

2024-08-06

Who can join

Age: 50 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Clinical diagnosis of mild cognitive impairment
• SPPB score ≥ 3 points
• Willingness to participate in the interventions and collaborate with the research team
• Must be able to provide informed consent (oral or written)

You may not qualify if…

• Severe dementia
• Severe comorbidity that negatively influences participation in the intervention
• Color blindness
• Fractures in the last three months

Where it is running

• University of Beira Interior — Covilha, Portugal (enrolling)

Full record on ClinicalTrials.gov

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