Persistent Post Surgical Pain After Total Knee Arthroplasty

Recruiting now · Not applicable

Conditions studied: Knee Arthropathy

In brief

Patients undergone total knee replacement are randomized to receive a "fast track" regional anesthesia protocol or a "traditional" regional anesthesia continuous infusion by both a femoral and sciatic catheter to assess if this latter technique may reduce persistent postoperative pain six months after surgery

Key facts

Study ID

NCT06182059

Run by

Policlinico di Monza SpA

People needed

436

Starts

2024-01-12

Expected to finish

2027-07-31

Last updated by the study team

2025-06-03

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• primary total knee replacement with a written informed consent

You may not qualify if…

• Allergy to local anesthetics or any drugs involve in the study
• Controindication to regional anesthesia
• chronic use of opioids
• BMI > 35 kg m2

Where it is running

• Policlinico di Monza SPA — Monza, Monza Brianza, Italy (enrolling)

Full record on ClinicalTrials.gov

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