Yangxinshi Tablet Intervention for Exercise Capacity in Patients With Chronic Coronary Syndrome

Recruiting now · Phase 4

Conditions studied: Chronic Coronary Syndrome

In brief

This study is a prospective, multicentre, randomized, open-label, blinded-endpoint clinical trial to evaluate the efficacy and safety of Yangxinshi tablets in the treatment of patients with chronic coronary syndrome (CCS).

Key facts

Study ID

NCT06171061

Run by

Shandong First Medical University

People needed

1200

Starts

2023-12-18

Expected to finish

2026-12-31

Last updated by the study team

2024-04-17

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• age 18-75 years;
• CCS patients in stable condition and clearly diagnosed by coronary artery imaging (at least one vessel stenosis ≥ 50%): stable angina, ischaemic cardiomyopathy, asymptomatic or stable symptoms, occult coronary heart disease, acute coronary syndrome (ACS), or >3 months after coronary revascularization;
• moderately to severely limited exercise tolerance: the maximum 6MWD is < 450 m, or the metabolic equivalent (MET) as measured by treadmill cardiopulmonary exercise testing is < 5 METs;
• voluntary participation and signing of informed consent.

You may not qualify if…

• absolute or relative contraindications for the treadmill cardiopulmonary exercise test or 6-minute walk test (6MWT);
• serious primary diseases, mental diseases, or malignant tumours that affect lifespan;
• pregnancy, intended or suspected pregnancy, miscarriage, breastfeeding, or delivery in the last 6 months;
• subjects not suitable for this study in the opinion of the researchers, such as subjects who are participating in other drug clinical trials or intervention studies.

Where it is running

• Affiliated Hospital of Qingdao University — Qingdao, Shandong, China (enrolling)
• Hospital of Cardiovascular Diseases Affiliated to Qingdao University — Qingdao, Shandong, China (enrolling)
• Affiliated Hospital of Shandong University of Traditional Chinese Medicine — Jinan, Shandong, China (enrolling)
• Feicheng People's Hospital — Feicheng, Shandong, China (enrolling)
• Shandong Health Group Feicheng Hospital — Feicheng, Shandong, China (enrolling)
• Shandong Provincial Hospital Affiliated to Shandong First Medical University — Jinan, Shandong, China (enrolling)
• Jinan Central Hospital — Jinan, Shandong, China
• Jinan Zhangqiu District People's Hospital — Jinan, Shandong, China
• The Fourth People's Hospital of Jinan — Jinan, Shandong, China
• Gaotang County People's Hospital — Liaocheng, Shandong, China
• Liaocheng Hospital of Traditional Chinese Medicine — Liaocheng, Shandong, China
• Liaocheng People's Hospital — Liaocheng, Shandong, China
• The Second People's Hospital of Liaocheng — Liaocheng, Shandong, China
• Linqing City People's Hospital — Linqing, Shandong, China
• Linyi People's Hospital — Linyi, Shandong, China
• Longkou People Hosptial — Longkou, Shandong, China
• Qingdao Central Hospital — Qingdao, Shandong, China
• Qingdao Fuwai Hospital — Qingdao, Shandong, China
• Qingdao Municipal Hospital — Qingdao, Shandong, China
• Shandong University Qilu Hospital Qingdao District — Qingdao, Shandong, China
• The Second Affiliated Hospital of Shandong First Medical University — Taian, Shandong, China
• Xintai People's Hospital — Taian, Shandong, China
• Tengzhou Central People's Hospital — Tengzhou, Shandong, China
• Weifang City People's Hospital — Weifang, Shandong, China
• Weifang City Yidu Central Hospital — Weifang, Shandong, China

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.