Effect of Individualized PEEP on Postoperative Pulmonary Complication in Bariatrics

Recruiting now · Not applicable

Conditions studied: Mechanical Ventilation Pressure High, Bariatric Surgery Candidate

In brief

Ventilation with low tidal volume and high PEEP (positive end expiratory pressure) has been shown to improve oxygenation in patients with ARDS (acute respiratory distress syndrome). In obese patients undergoing laparoscopic bariatric surgeries, the risk of postoperative pulmonary complications (PPCs) increases significantly with general anesthesia. Previous studies have shown that protective lung ventilation strategies could improve intraoperative oxygenation and lung mechanics. In this study would compare the effect of optimum individualized high PEEP versus standard PEEP - on postoperative pulmonary complications

Key facts

Study ID

NCT06168162

Run by

Ain Shams University

People needed

50

Starts

2023-10-01

Expected to finish

2025-05-01

Last updated by the study team

2025-02-17

Who can join

Age: 16 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients were eligible for participation if the met the following criteria
• Age between 18 and 60 years old.
• Body mass index > 40
• Laparoscopic bariatric elective surgery under general anesthesia.
• ARISCAT (Assess Respiratory Risk in Surgical Patients in Catalonia) score ≥ 45 . ARISCAT score is a clinically practical seven-factor scoring system to assess the risk of a composite PPC.

You may not qualify if…

• Previous lung surgery
• ASA status III or IV.
• Moderate to severe obstructive or restrictive lung disease .
• Persistant intraoperative hemodynamic instability .
• Need for postoperative mechanical ventilation

Where it is running

• Ain shams university — Cairo, Cairo Governorate, Egypt (enrolling)

Full record on ClinicalTrials.gov

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