Developing Allogeneic Musculoskeletal Therapies

Recruiting now

Conditions studied: Osteoarthritis

In brief

The goal of this observational study is to analyse the cartilage and bone forming potential of cells isolated from the tissues of patients undergoing surgery for the treatment of polydactyly, hip dislocation and from other bio-banked cartilage tissues. The main question it aims to answer is: Which of the following tissues from polydactyly digit, iliac apophysis or other bio-banked cartilage produce better cartilage in vitro and in vivo? Participants receiving digit amputation surgery for treatment of polydactyly will be asked to donate the associated waste tissue whilst participants receiving surgery to treat a dislocated hip will be asked to donate an extra small piece of cartilage tissue (approximately 1 gram) from the iliac apophysis. Other tissues for the study will be obtained from those donated to biobanks.

Key facts

Study ID

NCT06167928

Run by

Keele University

People needed

325

Starts

2018-10-08

Expected to finish

2037-09-01

Last updated by the study team

2026-06-11

Who can join

Age: any. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• For juvenile/infant donors:
• Parents/guardians being able to provide signed and dated informed consent form.
• Scheduled for one of the following surgical treatments:
• Digit amputations due to polydactyly. Surgery to treat dislocated hips.
• For biobank/NHSBT donors
• Informed consent via consenting institution.

You may not qualify if…

• Parents/guardians not understanding the Patient Information Sheet

Where it is running

• Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust — Oswestry, Shropshrie, United Kingdom (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.