Current Practice of Ventilation Strategies in Children Undergoing General Anesthesia
Recruiting now
Conditions studied: Mechanical Ventilation Complication, Pediatric ALL, Pulmonary Complication, Perioperative/Postoperative Complications
In brief
Postoperative pulmonary complications (PPCs) are common in children undergoing general anesthesia and are associated with prolonged stay in the hospital and high costs. Development of PPCs is associated with ventilator settings in adult patients undergoing general anesthesia. Data on perioperative ventilator settings in children are lacking, leaving the anaesthetist without guidance. Consequently, the current standard of care in perioperative mechanical ventilation in children is expected to be extremely heterogeneous, leading to ventilation with higher levels of energy than necessary. Therefore, it is highly necessary to evaluate the current practice in perioperative ventilation in children and to determine associations with PPCs.
Key facts
- Study ID
- NCT06166706
- Run by
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
- People needed
- 10000
- Starts
- 2024-01-29
- Expected to finish
- 2026-01-07
- Last updated by the study team
- 2025-04-09
Who can join
Age: any, up to 16. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- aged ≤ 16 years;
- undergoing general anesthesia
- airway management with tube or LMA; and
- connected to mechanical ventilator . minimum duration of procedure: 15 minutes
You may not qualify if…
- patients undergoing surgical procedures involving extra-corporal circulation;
- patients receiving ventilation with high frequency jet ventilation or high frequency oscillatory ventilation;
- sedation without airway management in the form of a endotracheal tube or a supraglottic airway device; and
- (rigid) bronchoscopic procedures with maintenance of spontaneous ventilation.
Where it is running
- Amsterdam University Medical Centers — Amsterdam, Please Select, Netherlands (enrolling)
- Perth Children's Hospital — Perth, Australia
- IRCCS Istituto Giannina Gaslini — Genoa, Italy
- Universitatsspital Bern — Bern, Switzerland
Full record on ClinicalTrials.gov
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