Laryngeal and Vocal Tract Strategies to Reduce Vocal Fold Contact Pressure
Recruiting now · Not applicable
Conditions studied: Mid-membranous Vocal Fold Lesion
In brief
Phonotraumatic vocal hyperfunction is one of the most frequently occurring conditions to affect the voice. This voice disorder often involves vocal fold injury due to repeated, excessive contact pressure between the vocal folds when they collide during voice production. In the clinic, voice therapy attempts to modify unhealthy vocal behaviors through different techniques or exercises. While voice therapy is generally considered effective, the scientific rationale for its therapeutic benefits still remains unclear. It is generally believed that these exercises lead to adjustments in the larynx and vocal tract that reduce vocal fold contact pressure. However, this assumption has never been tested in humans or laboratory experiments. The goal of this clinical trial is to investigate the effectiveness of voice therapy in reducing vocal fold contact pressures and in eliciting the hypothesized favorable laryngeal and vocal tract configurations.
Key facts
- Study ID
- NCT06165536
- Run by
- University of California, Los Angeles
- People needed
- 60
- Starts
- 2025-12-01
- Expected to finish
- 2028-01-31
- Last updated by the study team
- 2025-12-15
Who can join
Age: 18 and older, up to 40. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Ages 18-40 years (to minimize developmental changes associated with adolescent and elderly age)
- Clinic diagnosis by a fellowship trained laryngologist of mid-membranous lesions that by history and appearance are phonotraumatic
- Must be referred for voice therapy
You may not qualify if…
- Medical comorbidities (e.g., autoimmune disorders) beyond seasonal allergy and laryngopharyngeal reflux
- Vocal fold lesions generally regarded to be less responsive to voice therapy (e.g. vocal fold cysts).
- Claustrophobia
- Inability to replicate fundamental frequencies required for the study at the intensity levels determined
Where it is running
- UCLA Rehab Center — Los Angeles, California, United States (enrolling)
Full record on ClinicalTrials.gov
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