Chronic Endometritis and Benefits of Antibiotics in Women With Recurrent Miscarriage

Recruiting now

Conditions studied: Recurrent Miscarriage

In brief

The aim of the study is to estimate the incidence of CE, evaluate the endometrial microorganism of CE, and investigate the therapeutic benefits of antibiotics for women with unexplained recurrent miscarriage and CE.

Key facts

Study ID

NCT06163092

Run by

Chinese University of Hong Kong

People needed

175

Starts

2024-04-01

Expected to finish

2027-01-31

Last updated by the study team

2025-03-20

Who can join

Age: 20 and older, up to 45. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Women with a history of 2 or more consecutive miscarriages before 24 weeks of gestation
• Women aged 20-45 years old

You may not qualify if…

• Uncorrected uterine anomalies, such as the septate or bicornuate uterus, fibroids (submucous/intramural)
• Untreated hydrosalpinx
• Antiphospholipid syndrome
• Known clinical autoimmune disease
• Undergoing immunotherapy
• Abnormal thyroid function
• Abnormal karyotyping of couples
• Known immunodeficiency pathologies such as diabetes or HIV
• Currently taking other antibiotics or other trial medications or TCM;
• Currently or previously involved in other clinical trials with medication intake;
• Those with active pelvic inflammatory disease or suspicion of infection etc.

Where it is running

• The Chinese University of Hong Kong — Hong Kong, Hong Kong (enrolling)

Full record on ClinicalTrials.gov

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