Connective Tissue Matrix for Rotator Cuff Tendinopathy

Running, not enrolling · Phase 4 · Has a placebo group

Conditions studied: Tendinopathy, Shoulder Pain, Rotator Cuff Tendinitis, Rotator Cuff Tendinosis

In brief

The purpose of this research study is to determine if the effectiveness of a single injection of CTM Boost in the treatment of patients with rotator cuff tendinopathy (RCT) is as effective as a single injection of platelet rich plasma (PRP) in reducing the symptoms of RCT.

Key facts

Study ID: NCT06160427
Run by: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
People needed: 92
Starts: 2023-12-04
Expected to finish: 2028-01-15
Last updated by the study team: 2025-09-08

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Patients aged 18-80 years old with rotator cuff tendinopathy
A PRP or CTM-type injection was determined by the clinician to be the proper medical treatment course and patient is willing to undergo the injection

You may not qualify if…

Patients with adhesive capsulitis
Patients with acromio-clavicular joint impingement, retracted tears, significant labral lesions or significant glenohumeral arthrosis
Patients with joint instability
History of shoulder surgery or corticosteroid injection in the past 3 months
Patients with any medical conditions that affect healing, such as end-stage renal disease or uncontrolled diabetes

Where it is running

Allegheny Health Network Allegheny General Hospital — Pittsburgh, Pennsylvania, United States
Allegheny Health Network Federal North Medical Office Building — Pittsburgh, Pennsylvania, United States
AHN Wexford Health & Wellness Pavilion — Wexford, Pennsylvania, United States
AHN Wexford Hospital — Wexford, Pennsylvania, United States

Full record on ClinicalTrials.gov

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