SARcopenia and Simplified Geriatric Assessment in Lymphoma Patients Undergoing CAR-T Cell Therapy: the FIL_SAR-CAR Project

Recruiting now

Conditions studied: Non-hodgkin Lymphoma,B Cell

In brief

This is a multicenter prospective observational study lead by the FIL on sarcopenia and sGA as possible predictors of efficacy and toxicity outcomes in patients undergoing CAR-T cells treatment.

Key facts

Study ID

NCT06156774

Run by

Fondazione Italiana Linfomi - ETS

People needed

130

Starts

2024-04-18

Expected to finish

2026-07-01

Last updated by the study team

2025-12-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients (≥ 18 years old).
• Patients with B-cell non-Hodgkin Lymphoma scheduled to received CAR-T cell product according to Agenzia Italiana del Farmaco (AIFA) indications and technical data sheet of the drug
• Availability of a 18F-FDG PET/CT scan or a full dose CT scan (without contrast media) pre-treatment with CART
• Written informed consent voluntarily provided

You may not qualify if…

• Patients not fulfilling the eligibility criteria

Where it is running

• ULSS 8 Berica - Ospedale S. Bortolo - Ematologia — Vicenza, Italy (enrolling)
• AOU Ospedali Riuniti - Clinica di Ematologia — Ancona, Italy (enrolling)
• Azienda Ospedaliera S .Giuseppe Moscati - S.C. Ematologia e Trapianto emopoietico — Avellino, Italy (enrolling)
• IRCCS Centro di Riferimento Oncologico di Aviano - Divisione di Oncologia e dei Tumori immuto-correlati — Aviano, Italy (enrolling)
• ASST Spedali Civili di Brescia - S.C. Ematologia — Brescia, Italy (enrolling)
• Ospedale di Castelfranco Veneto - Oncoematologia IOV — Castelfranco Veneto, Italy (enrolling)
• Azienda Ospedaliera Universitaria Careggi - Unità funzionale di Ematologia — Florence, Italy (enrolling)
• ASST Grande Ospedale Metropolitano Niguarda - S.C. Ematologia — Milan, Italy (enrolling)
• Fondazione IRCCS Istituto Nazionale dei Tumori di Milano - Ematologia — Milan, Italy (enrolling)
• Istituto Scientifico San Raffaele - Unità Linfomi - Dipartimento Oncoematologia — Milan, Italy (enrolling)
• A.O. Ospedali Riuniti Villa Sofia-Cervello - Divisione di Ematologia — Palermo, Italy (enrolling)
• Ospedale S. Maria della Misericordia - Ematologia — Perugia, Italy (enrolling)
• Ospedale Guglielmo da Saliceto - U.O. Ematologia — Piacenza, Italy (enrolling)
• A.O. SS. Antonio e Biagio e Cesare Arrigo - S.C.D.U. Ematologia — Alessandria, Italy (enrolling)
• Azienda Unità Sanitaria Locale-IRCCS - Arcispedale Santa Maria Nuova - Ematologia — Reggio Emilia, Italy (enrolling)
• Fondazione Policlinico Universitario A. Gemelli IRCCS - Università Cattolica S. Cuore - Ematologia — Roma, Italy (enrolling)
• Policlinico Umberto I - Università "La Sapienza" - Istituto Ematologia -Dipartimento di Medicina Traslazionale e di Precisione — Roma, Italy (enrolling)
• A.O.U. Citta della Salute e della Scienza di Torino - S.C. Ematologia — Torino, Italy (enrolling)
• Azienda Sanitaria Universitaria Friuli Centrale (ASU FC) - Clinica di Ematologia — Udine, Italy (enrolling)
• AOU Integrata di Verona - U.O. Ematologia — Verona, Italy (enrolling)
• AOU Pisana - U.O. Ematologia — Pisa, Italy

Full record on ClinicalTrials.gov

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