Intraoperative Echocardiography in Low-Risk CABG Surgery

Completed · Not applicable

Conditions studied: Heart Diseases, Coronary Artery Disease, Chest Pain, Stenosis Coronary, STEMI

In brief

This goal of this study is to better understand when and where intraoperative transesophageal echocardiography (TEE) should (or should not) be used during coronary artery bypass graft (CABG) surgeries.

Key facts

Study ID

NCT06154265

Run by

University of Pennsylvania

People needed

40

Starts

2024-01-22

Expected to finish

2026-03-15

Last updated by the study team

2026-05-12

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Scheduled to undergo isolated CABG surgery at a hospital within the UPenn Health System
• Age ≥18 years
• Ejection fraction ≥50%
• Transthoracic echocardiography within one year of scheduled surgery date
• Left heart catheterization within one year of scheduled surgery date
• English language fluency or facilitated via language interpreter
• Able to provide informed consent either in English or via a language interpreter
• Willing to comply with all study procedures

You may not qualify if…

• Documented valve (aortic, mitral, tricuspid, or pulmonic) disease (stenosis or regurgitation) moderate or greater.
• Any CABG surgery with either "possible" or "definite" aortic intervention listed as a planned part of the procedure. plan for either definite or possible surgical intervention.
• Any CABG surgery with either "possible" or "definite" valve repair/replacement listed as a planned part of the procedure.
• Having undergone any previous cardiac surgeries (i.e. scheduled with a "REDO" modifier).
• Proximal/critical left main coronary disease (e.g. greater than or equal to 90% stenosis).
• Preexisting anomalous coronary arteries
• Preexisting end-stage renal disease on hemodialysis
• Preexisting chronic kidney disease (CKD) stage 3, 4, or 5
• Stroke with residual focal neurological deficit(s) within 90 days of surgery
• Any of the following presurgical, mechanical circulatory support devices:
• Intraaortic balloon pump
• Percutaneous right ventricular assist device (RVAD)
• Impella
• Extracorporeal membrane oxygenation (ECMO)
• Absolute contraindication to echocardiography defined as one or more of the following documented conditions:
• Esophagectomy
• Esophagogastrectomy
• Esophageal trauma
• Any of these three relative contraindication to TEE:
• Esophageal varies
• Gastric bypass surgery
• Descending thoracic aortic aneurysm
• Severe pulmonary hypertension defined as:
• Pulmonary arterial pressure ≥60 mmHg
• Pulmonary vascular resistance (PVR) ≥3 Woods Units

Where it is running

• Hospital of the University of Pennsylvania — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.