Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings

Recruiting now · Not applicable

Conditions studied: Suicide, Attempted, Suicide Ideation, Suicide, Suicide Prevention

In brief

The study will compare the effectiveness of two relatively brief and scalable evidence-based interventions: the Stanley Brown Safety Planning Intervention and Follow-up Contacts (SPI+), a suicide-specific intervention that helps people prevent suicidal crises from escalating, and Interpersonal Psychotherapy for Adolescents Ultra Short Crisis Intervention (IPT-A SCI), a psychotherapeutic crisis intervention treatment for suicidal adolescents that teaches youth skills to prevent suicidal crises and addresses interpersonal problems that lead to suicidal crises. The results will inform the future standard of care for youth at risk for suicide presenting in the ED setting. This project focuses on suicidal youth ages 12-24 in five ethnically and racially diverse urban areas: Philadelphia, Pennsylvania; Baltimore, Maryland; Chapel Hill, North Carolina; St. Petersburg, Florida; and Northern Manhattan/lower Bronx/eastern Queens communities in New York City, New York.

Key facts

Study ID: NCT06151158
Run by: Johns Hopkins University
People needed: 484
Starts: 2025-03-10
Expected to finish: 2029-08-15
Last updated by the study team: 2026-07-08

Who can join

Age: 12 and older, up to 24. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Suicide Risk During Acute Care Visit (At least one item in risk assessment is required; check all that apply): ___ Chief complaint of suicide-related concern (via Medical Record/Other), ___ Active suicidal ideation endorsed in past 1 month on validated suicide screener, ___ Suicidal behavior in the past 3 months on validated suicide screener, ___ Clinician indicated SI in past month or SA in past 3 months.
Have access to a cellular phone with the ability to receive phone calls and text messages over the 12-month follow- up period
Adolescent must be verbally fluent and can communicate, understand, and read in either English or Spanish
Adolescent has been/will be discharged from a higher level of care (i.e. inpatient, day hospital, partial hospitalization program (PHP), or residential treatment program) and back in the community within 4 weeks of their acute care visit. [Note: this criterion does not apply to all patients - select N/A if this is the case.

You may not qualify if…

Significant cognitive or developmental delays that prevent understanding or using SPI+ or IPT-A-SCI (includes inability to communicate verbally)
Altered mental status (acute psychosis, intoxication, or mania)
Unable or unwilling to provide informed consent (adults), assent (minors), or permission (parents/caregivers)
The services offered through the study are not in the best clinical interest of the patient (e.g., presenting problem requires a different level of care or treatment approach).

Where it is running

Johns Hopkins All Children's Hospital — St. Petersburg, Florida, United States (enrolling)
Johns Hopkins University — Baltimore, Maryland, United States (enrolling)
Columbia University Irving Medical Center (CUMC) — New York, New York, United States (enrolling)
Weill-Cornell Medicine — New York, New York, United States (enrolling)
University of North Carolina Medical Center — Chapel Hill, North Carolina, United States (enrolling)
Childrens Hospital of Philadelphia — Philadelphia, Pennsylvania, United States (enrolling)

Full record on ClinicalTrials.gov

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