68Ga-FAPI PET/CT Imaging for Diagnosis, Grading, and Efficacy Evaluation of Myelofibrosis.
Recruiting now
Conditions studied: Primary Myelofibrosis
In brief
To evaluate the diagnostic efficacy of 68Ga FAPI PET/CT in myelofibrosis and to identify fibrosis grades. To evaluate the diagnostic efficacy of 68Ga FAPIPET/CT imaging in patients with myelofibrosis, compared with conventional CT.
Key facts
- Study ID
- NCT06151119
- Run by
- The First Affiliated Hospital of Xiamen University
- People needed
- 90
- Starts
- 2023-11-22
- Expected to finish
- 2027-06-30
- Last updated by the study team
- 2025-02-19
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age ≥18 years old;
- Cohort 1: Patients with suspected or confirmed myelofibrosis; Cohort 2: Patients with primary/secondary myelofibrosis who were not treated with ruxolitinib.
- The expected survival time is over 3 months
- Voluntarily sign informed consent.
- Willing and able to follow the research protocol;
- The subject must be able to lie on the scanning bed for 20 minutes;
You may not qualify if…
- Known allergic history to 68Ga FAPI or its excipients;
- Patients who can not tolerate intravenous drug administration (such as needle fainting and blood fainting history);
- Those who are not suitable for or unable to complete imaging tests such as PET due to special reasons, including claustrophobia and radiophobia;
- pregnant and lactating women;
- Workers who are exposed to radiation for a long period of time;
- Serious diseases of the heart, kidney, lung, blood vessel, nervous system, mental system, immune deficiency diseases and hepatitis/cirrhosis;
- Participating in other interventional clinical trials within 1 month before screening;
- Patients undergoing chemotherapy, immunotherapy or molecular targeted therapy due to other cancers;
- There are other circumstances that the researcher thinks are not suitable for participating in this study;
Where it is running
- Bing Xu — Xiamen, Fujian, China (enrolling)
Full record on ClinicalTrials.gov
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