Manual Therapy on Oral Opening, Swallow Function and Upper Quarter Mobility on Head and Neck Cancer Survivors

Recruiting now · Not applicable

Conditions studied: Head and Neck Cancer, Trismus, Dysfunction

In brief

Trismus has been reported as the second most common comorbidity in survivors of head and neck cancer (HNC). It is mainly associated with post-radiotherapy subcutaneous fibrosis, muscular atrophy, damage to neurological structures in the neck, or a combination of all, affecting masticatory musculature. In addition to this, the loss of flexibility and strength in the shoulder has also been shown to be related to deficits in the function and quality of life of these patients. The goal of this clinical trial is to determinate the effectiveness and safety of Manual Therapy (MT) on Oral Opening, Swallow Function, as well as the mobility of the upper quarter, the strength of cervical musculature, pain, functionality, and the perception of quality of life in head and neck cancer survivors. Participants will be assigned randomly to the study groups: a) manual therapy program and control motor exercises and b) motor control exercises (usual care). The assessment refers to a baseline form (at the beginning of the study), at 6 weeks and at 6 weeks of patient follow-up.

Key facts

Study ID

NCT06148077

Run by

Universidad de La Frontera

People needed

70

Starts

2024-09-25

Expected to finish

2025-10-01

Last updated by the study team

2025-05-30

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• individuals with HNC
• individuals over 18 years of age
• individuals who have undergone oncological surgery of the head and neck and/or radiotherapy
• having finished oncological medical treatment between 3 and 36 months before inclusion
• having a medical diagnosis of trismus and/or TMD and/or cervical or shoulder dysfunction
• Spanish native speakers

You may not qualify if…

• sequelae of previous stroke
• structural instability and/or osteoporosis of the cervical spine, spondylosis, cervical herniated discs
• active osteoradionecrosis or open wounds (fistulas, soft tissue necrosis) in the anatomical treatment area
• tracheostomized individuals
• metastasis or active cancer
• refuse to participate.

Where it is running

• Barbara Burgos Mansilla — Temuco, Cautin, Chile (enrolling)
• Universidad de La Frontera — Temuco, Cautin, Chile (enrolling)

Full record on ClinicalTrials.gov

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