Diagnosing Vesicoureteric Reflux in Children by Direct Isotope Cystography and Contrast Enhanced Voiding Ultrasonography

Recruiting now · Not applicable

Conditions studied: VUR - Vesicoureteric Reflux

In brief

The purpose of this study is to examine the applicability of contrast enhanced voiding ultrasonography in diagnosing vesicoureteral reflux (VUR) in pediatric patients compared to direct isotope cystography. The aim of the study is to find a modality allowing the accurate diagnosis of VUR and the classification of the degree of VUR with the least possible harm from the examinations. The investigators recruit 100 under 6 years old patients who have had at least 2 culture positive urinary tract infections. Exluding criteria are abnormal bladder function and posterior uretral valves. The investigators perform direct isotope cystography and contrast enhanced voiding urosonography during the same day to diagnose and grade VUR. The investigators use standardized volume and speed of bladder filling. The examinations are done by a radiologist and an isotope specialist and they are blinded to the result of the other examination.

Key facts

Study ID

NCT06138080

Run by

Turku University Hospital

People needed

100

Starts

2022-05-15

Expected to finish

2031-05-01

Last updated by the study team

2023-11-18

Who can join

Age: any, up to 6. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• under 6 years old patients who have had at least 2 culture positive urinary tract infections

You may not qualify if…

• abnormal bladder function
• posterior uretral valves

Where it is running

• Turku University hospital — Turku, Finland (enrolling)

Full record on ClinicalTrials.gov

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