Cognitive Rehabilitation in Post-COVID-19 Syndrome
Completed · Not applicable
Conditions studied: Post-COVID-19 Syndrome
In brief
The first aim of this study is to determine the feasibility of delivering CO-OP remotely to individuals experiencing cognitive impairments that limit everyday activities in post-COVID-19 syndrome (PCS). The second aim of this study is to assess the effect of CO-OP on activity performance, subjective and objective cognition, and quality of life in a sample of individuals with PCS. The research team hypothesizes that effect size estimations will indicate that CO-OP will have a greater positive effect, compared to an inactive control group, on activity performance, subjective and objective cognition, and quality of life in a sample of individuals who self-report PCS and cognitive impairment.
Key facts
- Study ID
- NCT06136871
- Run by
- University of Missouri-Columbia
- People needed
- 65
- Starts
- 2024-02-01
- Expected to finish
- 2025-06-30
- Last updated by the study team
- 2026-03-13
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- self-reported cognitive symptoms persisting for at least 6 weeks following COVID-19 infection (Cognitive Failures Questionnaire (CFQ) score >43)
- self-identified activity performance goals per the Canadian Occupational Performance Measure (COPM)
- documented prior diagnosis of COVID-19
- read, write, and speak English fluently
- ability to provide valid informed electronic consent
You may not qualify if…
- diagnosis of severe neurological or psychiatric condition(s)
- dementia symptoms as indicated by a score of <23 on the Montreal Cognitive Assessment (MoCA)
- untreated sleep apnea (≥5 on the STOPBANG)
- prior cancer treatment
- severe depressive symptoms (>21 on the Patient Health Questionnaire-9)
Where it is running
- University of Missouri Department of Occupational Therapy — Columbia, Missouri, United States
Full record on ClinicalTrials.gov
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