A Study to Investigate the Safety and Tolerability of LY3938577 in Healthy Participants and Participants With Type 2 Diabetes Mellitus
Completed · Phase 1 · Has a placebo group
Conditions studied: Healthy, Type 2 Diabetes Mellitus
In brief
The main purpose of this study is to assess the safety and tolerability of a single dose of LY3938577 in healthy participants and participants with Type 2 Diabetes Mellitus (T2DM) (Part A) and multiple doses of LY3938577 in participants with T2DM (Part B). The study will last approximately 6 weeks for Part A and approximately 10 weeks for Part B respectively.
Key facts
- Study ID
- NCT06132126
- Run by
- Eli Lilly and Company
- People needed
- 66
- Starts
- 2023-11-17
- Expected to finish
- 2024-06-28
- Last updated by the study team
- 2024-07-24
Who can join
Age: 18 and older, up to 70. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Male and female participants who are overtly healthy as determined by medical evaluation (Part A)
- Participants with T2DM diagnosed greater than 1 year before enrollment (Part A and Part B)
- Have a body mass index within the range of 18.5 to less than or equal to (<=) 32 kilograms per square meter (kg/m²) for healthy participants and 18.5 to 40 kg/m² for T2DM participants.
- Male or female participants of nonchildbearing potential
You may not qualify if…
- Have proliferative retinopathy or maculopathy and/or severe neuropathy
- Have been treated with sulfonylurea, thiazolidinedione, alpha-glucosidase inhibitor, glucagon-like peptide-1 receptor agonist or Insulin within the previous 3 months
- Have received chronic systemic glucocorticoid therapy in the past 3 months
- Are currently enrolled in another clinical study trial involving medical research, or have participated within the last 30 days in a clinical study involving an investigational product.
Where it is running
- CenExel ACT — Anaheim, California, United States
- Qps-Mra, Llc — Miami, Florida, United States
- Labcorp CRU — Dallas, Texas, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.