Study to Evaluate the Pharmacokinetics, Safety and Tolerability of Intravenous Secukinumab in Patients With GCA or PMR
Completed · Phase 1
Conditions studied: Giant Cell Arteritis, Polymyalgia Rheumatica
In brief
This study will examine how intravenous (i.v.) Secukinumab will be processed in the body (pharmacokinetics \[PK\]) and whether it will be safe and tolerable after multiple doses of i.v. Secukinumab infusion in adult patients with giant cell arteritis (GCA) or polymyalgia rheumatica (PMR).
Key facts
- Study ID
- NCT06130540
- Run by
- Novartis Pharmaceuticals
- People needed
- 65
- Starts
- 2024-03-27
- Expected to finish
- 2025-04-02
- Last updated by the study team
- 2026-04-01
Who can join
Age: 50 and older, up to 100. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Rheumatology Associates of South Florida — Boca Raton, Florida, United States
- FL Medical Clinic Orlando Health — Zephyrhills, Florida, United States
- Willow Rheumatology Wellness — Willowbrook, Illinois, United States
- Altoona Center for Clin Res — Duncansville, Pennsylvania, United States
- West Tennessee Research Institute — Jackson, Tennessee, United States
- Accurate Clinical Research Inc — San Antonio, Texas, United States
- Overlake Internal Med Associates — Bellevue, Washington, United States
- Rheumatology Pulmonary Clinic — Beckley, West Virginia, United States
- Novartis Investigative Site — Uherské Hradiště, Uherske Hradiste, Czechia
- Novartis Investigative Site — Brno-Bohunice, Czechia
- Novartis Investigative Site — Florence, FI, Italy
- Novartis Investigative Site — Reggio Emilia, RE, Italy
- Novartis Investigative Site — Lisbon, Portugal
- Novartis Investigative Site — Santiago de Compostela, Galicia, Spain
- Novartis Investigative Site — Madrid, Spain
- Novartis Investigative Site — Madrid, Spain
- Novartis Investigative Site — Basel, Switzerland
- Novartis Investigative Site — Bern, Switzerland
- Novartis Investigative Site — Sankt Gallen, Switzerland
Full record on ClinicalTrials.gov
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