Exercise CMR in (p)LF-LG AS

Recruiting now

Conditions studied: Aortic Stenosis, Severe

In brief

Patient with paradoxical or conventional low-flow low-gradient aortic stenosis on echocardiographic assessment will undergo physiological exercise-stress CMR in addition to guideline recommended surveys prior to TAVR.

Key facts

Study ID

NCT06129799

Run by

University of Göttingen

People needed

100

Starts

2023-11-01

Expected to finish

2026-12-31

Last updated by the study team

2023-11-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• paradoxical or conventional severe low-flow low-gradient aortic stenosis

You may not qualify if…

• CMR incapable device
• unable to undergo 40 min scan (can not lie flat, claustrophobia)
• renal insufficiency (eGFR <30 ml/min/1.73m²)
• allergy against contrast agent
• unable to exercise in supine position

Where it is running

• University Hospital Goettingen — Göttingen, Germany (enrolling)

Full record on ClinicalTrials.gov

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