Basal Instincts: Towards Better Understanding of Basal Cell Function in Chronic Rhinosinusitis With Nasal Polyps

Recruiting now

Conditions studied: Chronic Rhinosinusitis With Nasal Polyps, Allergic Rhinitis

In brief

During this project, the investigators want to explore in vitro changes in basal cells and the crosstalk with residing immune cells as potential pathogenic mechanisms in CRSwNP vs healthy controls by using surgically resected patient samples.

Key facts

Study ID

NCT06129552

Run by

Universitaire Ziekenhuizen KU Leuven

People needed

300

Starts

2023-12-19

Expected to finish

2027-12-01

Last updated by the study team

2024-03-22

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients over the age of 18
• Males and females

You may not qualify if…

• CRSwNP
• AR
• Smoker, or < 1-year ex-smoker
• Underlying systematic pathology (Morbus Wegener or Churg Strauss Syndrome for example)

Where it is running

• Peter Hellings — Leuven, Belgium (enrolling)

Full record on ClinicalTrials.gov

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