Guided Episodic Future Thinking to Increase Physical Activity Adherence and Promote Healthy Brain Aging
Recruiting now · Not applicable
Conditions studied: Exercise Training, Aging
In brief
The goal of this behavioral clinical trial is to learn how to increase physical activity in mid-life adults. Specifically, can guided imagery that includes creating mental pictures increase excitement about working out. Participants will be asked to complete testing at the beginning of the study, following 6-weeks of an in-person exercise program, and 6-weeks after finishing the exercise program. Testing will include an exercise test, MRI, questionnaires, computer tasks, and a blood draw.
Key facts
- Study ID
- NCT06123182
- Run by
- University of Kansas Medical Center
- People needed
- 160
- Starts
- 2024-02-23
- Expected to finish
- 2027-05-01
- Last updated by the study team
- 2026-03-27
Who can join
Age: 45 and older, up to 65. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- speak English
- have access to reliable communication (a telephone or cell phone, computer, etc.)
- normal or corrected to normal vision and hearing
- ambulatory (without the use of assistive devices)
- physically underactive
- able to give informed consent
- able to exercise continuously on the recumbent stepper exercise device for 4 minutes greater than or equal to 25 watts to demonstrate ability to perform exercise on stepper \& no aerobic exercise contraindications or other safety/physical concerns
- able to communicate with investigators, follow 2-step command \& correctly answer consent comprehension questions
- stable blood pressure and statin medication doses for 30 days as these affect vascular health/hemodynamics
- willing and able to safely enter magnetic resonance (MR) scanner and attempt the MR scan
- willing and able to attempt a blood draw
You may not qualify if…
- patients with arrhythmias or acute cardiac events will be excluded due to potential complications with the supervised moderate exercise
- at risk for hazard due to magnetic fields due to MR safety concerns
- have any neurologic or psychiatric disorder except depression, anxiety (including post-traumatic stress disorder)
- have history of seizures or head trauma due to MR data quality
Where it is running
- University of Kansas Medical Center — Kansas City, Kansas, United States (enrolling)
Full record on ClinicalTrials.gov
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