AI-Powered Artificial Vision for Visual Prostheses
Enrolling by invitation · Not applicable
Conditions studied: Blindness, Acquired
In brief
Visual impairment is one of the ten most prevalent causes of disability and poses extraordinary challenges to individuals in our society that relies heavily on sight. Living with acquired blindness not only lowers the quality of life of these individuals, but also strains society's limited resources for assistance, care and rehabilitation. However, to date, there is no effective treatment for man patients who are visually handicapped as a result of degeneration or damage to the inner layers of the retina, the optic nerve or the visual pathways. Therefore, there are compelling reasons to pursue the development of a cortical visual prosthesis capable of restoring some useful sight in these profoundly blind patients. However, the quality of current prosthetic vision is still rudimentary. A major outstanding challenge is translating electrode stimulation into a code that the brain can understand. Interactions between the device electronics and the retinal neurophysiology lead to distortions that can severely limit the quality of the generated visual experience. Rather than aiming to one day restore natural vision (which may remain elusive until the neural code of vision is fully understood), one might be better off thinking about how to create practical and useful artificial vision now. The goal of this work is to address fundamental questions that will allow the development of a Smart Bionic Eye, a device that relies on AI-powered scene understanding to augment the visual scene (similar to the Microsoft HoloLens), tailored to specific real-world tasks that are known to diminish the quality of life of people who are blind (e.g., face recognition, outdoor navigation, reading, self-care).
Key facts
- Study ID
- NCT06117332
- Run by
- University of California, Santa Barbara
- People needed
- 7
- Starts
- 2023-10-02
- Expected to finish
- 2027-08-31
- Last updated by the study team
- 2025-07-31
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: accepted.
You may not qualify if…
- Visual prosthesis users: Subject is unwilling or unable to travel to testing facility for at least 3 days of testing within a one-week timeframe;
- Sighted controls: Subject has a history of motion sickness or flicker vertigo
- All: Subject has language or hearing impairment
Where it is running
- University of California, Santa Barbara — Santa Barbara, California, United States
- University Miguel Hernandez — Elche, Alicante, Spain
Full record on ClinicalTrials.gov
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