Immunoprofilling of Peripheral Blood Mononuclear Cells in Children With Attention Deficit/Hyperactivity Disorder

Recruiting now

Conditions studied: ADHD, Immune System, Clinical Syndrome

In brief

The goal of this observational study is to learn about The immune cell landscape of peripheral blood mononuclear cells in children with ADHD compared to typically developing controls. The main question it aims to answer are: 1.Testing the differences in immune cell subpopulations, protein expression and signaling pathways and cell subsets between two groups 2. Exploring the correlations between immune function in PBMC and resting-state brain functional networks in children with ADHD. Participants will be taken peripheral blood about 5 ml , cognitive assessment including Intelligence testing, Stroop color-word test and Trail making test, clinical interview and brain structural and functional MRI.

Key facts

Study ID

NCT06109337

Run by

First Affiliated Hospital of Zhejiang University

People needed

100

Starts

2023-12-04

Expected to finish

2027-12-01

Last updated by the study team

2025-04-01

Who can join

Age: 6 and older, up to 12. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Clinical diagnosis of ADHD； Children with an IQ≥70； Both parents are Han； Agree to take venous blood with informed consent；

You may not qualify if…

• Schizophrenia, mood disorder, autism, mental retardation； Obvious physical and nervous system abnormalities；

Where it is running

• Fu Guanghui — Hangzhou, Zhejiang, China (enrolling)

Full record on ClinicalTrials.gov

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