Erythrocyte Transport of Lactate During Exercise (TELE Project)

Recruiting now · Not applicable

Conditions studied: Energy Metabolism

In brief

The goals of this clinical trial are: 1. to study lactate kinetic between plasma and erythrocytes during an intervallic exercise and its subsequent recovery, considering the blood pH, the genotype for the T1470A polymorphism of the SLC16A1 gene (rs1049434), and the amount of MCT1 in erythrocytes membrane; 2. to analyze the levels of MCT1 in the erythrocytes membrane according to training status and genotype for the T1470A polymorphism of SLC16A1 (rs1049434). For this, the project will have two phases: * In phase I, trained participants will perform one maximal incremental test and one intervallic submaximal test with a final active recovery. * Phase II, levels of the MCT1 protein in the erythrocyte membrane will be quantified from trained and sedentary participants.

Key facts

Study ID

NCT06104150

Run by

Technical University of Madrid

People needed

84

Starts

2020-02-03

Expected to finish

2027-07-31

Last updated by the study team

2025-09-12

Who can join

Age: 18 and older, up to 30. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• BMI between 18 and 25 kg/m2
• Not smoker
• In the case of trained participants: training at least 5 hours/week, of which at least 3 must be aerobic/anaerobic endurance training. Presentation of a medical certificate attesting to their medical fitness (capability) to perform intense physical exercise.
• In the case of sedentary participants, less than 1 day of training per week or less than 2 hours of structured exercise per week.

You may not qualify if…

• Presenting any pathology that could impede the correct performance of the tests, or could influence the main study variables.
• In the case of the female sample, having irregular menstrual cycles, oligomenorrhea or amenorrhea.

Where it is running

• Laboratorio de Pediatría. School of Medicine. Univesidad de Cantabria — Santander, Cantabria, Spain (enrolling)
• Laboratorio de Fisiología del Esfuerzo. Facultad de Ciencias de la Actividad Física y del Deporte (INEF). Universidad Politécnica de Madrid — Madrid, Madrid, Spain (enrolling)

Full record on ClinicalTrials.gov

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