Biomarkers in Patients With Suspected HFpEF
Recruiting now
Conditions studied: Heart Failure, Obesity, Heart Failure With Preserved Ejection Fraction
In brief
NT-proBNP does not adequately identify HF(pEF) in people with suspected HF at low levels, particularly in patients with obesity. This study will investigate: 1. alternative cut-offs for NT-proBNP to identify HF(pEF) in people with suspected HF and obesity 2. novel candidate biomarkers to identify HF(pEF) in people with suspected HF and obesity. 3. novel candidate biomarkers to identify HF(pEF) in people with suspected HF and NT-proBNP \<125 ng/L 4. the prevalence of HF in people with suspected HF and low NT-proBNP \<125 ng/L)
Key facts
- Study ID
- NCT06101693
- Run by
- NHS Greater Glasgow and Clyde
- People needed
- 1028
- Starts
- 2023-02-02
- Expected to finish
- 2026-09-29
- Last updated by the study team
- 2024-02-13
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Written informed consent
- Age ≥ 18 years
- NT-proBNP sample taken by primary care physician as part of routine care for suspected heart failure
You may not qualify if…
- Unable to consent to inclusion in study due to significant cognitive impairment
- Geographical/ social reasons preventing attending study centre
- Unable to complete study assessments
- Patients presenting with acute HF or a previous diagnosis of HF
Where it is running
- Glasgow Royal Infirmary — Glasgow, United Kingdom (enrolling)
- New Victoria Hospital — Glasgow, United Kingdom (enrolling)
- Queen Elizabeth University Hospital — Glasgow, United Kingdom (enrolling)
Full record on ClinicalTrials.gov
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