Wrist Denervation Vs Exercise in Wrist Osteoarthritis

Recruiting now · Not applicable

Conditions studied: Osteoarthritis Wrist

In brief

A randomized controlled trial comparing partial wrist denervation to a self-managed exercise therapy program in 140 patients with wrist osteoarthritis.

Key facts

Study ID

NCT06098586

Run by

Karolinska Institutet

People needed

140

Starts

2023-11-15

Expected to finish

2027-11-15

Last updated by the study team

2025-02-21

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 18 years.
• Chronic wrist pain (≥6 months) due to Scapholunate advanced collapse (SLAC) / Scaphoid non-union advanced collapse (SNAC) grade 1-3 osteoarthritis.
• Radiological signs of osteoarthritis on posteroanterior and lateral radiograph.

You may not qualify if…

• Previous PIN or AIN neurectomy.
• Rheumatoid arthritis or other chronic inflammatory arthritis.
• Symptomatic osteoarthritis in the distal radio-ulnar (DRU), Scapho-trapezio-trapezoid (STT) or thumb carpometacarpal (CMC) joints.
• Ongoing infection.
• Inability to co-operate with the follow-up protocol.
• Systemic or intra-articular glucocorticoids or intraarticular PRP or Hyaluronic acid injections in the affected joint within 3 months prior to enrollment.

Where it is running

• Department of hand surgery, Malmo university hospital — Malmö, Sweden (enrolling)
• Department of hand handsurgery, Södersjukhuset — Stockholm, Sweden (enrolling)

Full record on ClinicalTrials.gov

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