Looking for a Blood Epigenetic Signature to Predict Female Infertility

Recruiting now

Conditions studied: Female Infertility

In brief

The present research project aims to study the DNAm mechanisms underlying the reduction of fertility due to the progressive depletion of oocyte quality. Specifically, our project aims to build an epigenetic clock for MGCs by using outcomes that are certainly related to female fertility. The validation of such findings will be carried out on peripheral blood in order to guarantee its non-invasiveness and allow for any clinical transferability. In order to identify a blood epigenetic signature able to predict female infertility, we planned to explore the problem from different points of view by conducting several studies in different settings.

Key facts

Study ID

NCT06098495

Run by

Università Vita-Salute San Raffaele

People needed

1456

Starts

2023-10-16

Expected to finish

2026-10-16

Last updated by the study team

2023-10-24

Who can join

Age: 18 and older, up to 43. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• 18< age <43, Infertile woman undergoing ART, recurrent pregnancy loss

You may not qualify if…

• age < 18 or > 44, previous ovarian surgery, severe male factor infertility

Where it is running

• Università Vita Salute San Raffaele — Milan, Italy (enrolling)

Full record on ClinicalTrials.gov

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