Effects of Change in Blood Pressure on Retinal Capillary Rarefaction in Patients With Arterial Hypertension

Recruiting now

Conditions studied: Arterial Hypertension, Blood Pressure, High

In brief

To evaluate whether in patients with initially poorly-controlled arterial hypertension, structural and functional differences in the retina and choroid remain after achieving a well-controlled blood pressure.

Key facts

Study ID

NCT06098300

Run by

Medical University of Vienna

People needed

30

Starts

2023-09-01

Expected to finish

2025-08-01

Last updated by the study team

2024-09-19

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Men and Women aged ≥ 18 years
• Signed informed consent
• Apart from hypertensive retinopathy, normal ophthalmic findings
• Non-Smokers
• Patients with initially diagnosed or pre-existing mild to moderate primary arterial hypertension (systolic office blood pressure ≥ 140 mmHg and/or diastolic office blood pressure ≥ 90 mmHg)
• Planned initiation of antihypertensive medication or planned adaption of antihypertensive medication by the Department of Cardiology
• Subject agrees to perform regular blood pressure self-measurements and to document blood pressure values in a diary

You may not qualify if…

• Participation in a clinical trial in the three weeks preceding the study
• Blood donation in the three weeks preceding the study
• Symptoms of a clinically relevant illness in the three weeks preceding the study
• History of family history of epilepsy
• Secondary hypertension (e.g.: hyperaldosteronism, pheochromocytoma, renal artery stenosis, renal parenchymal diseases, Cushing-syndrome, Coarctatio aortae)
• History of hypertensive encephalopathy or intracerebral bleeding
• Diabetes mellitus Type 1 or Type 2
• Pregnant or breast-feeding women
• Women of childbearing potential (neither menopausal, nor hysterectomized, nor sterilized) not using effective contraception

Where it is running

• Medical University of Vienna — Vienna, Austria (enrolling)

Full record on ClinicalTrials.gov

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