Non-invasive Brain Stimulation and Injury Risk Biomechanics
Completed · Not applicable · Has a placebo group
Conditions studied: Concussion, Mild
In brief
The goal of this clinical trial is to test the effects of repetitive transcranial magnetic stimulation (theta burst stimulation) on movement biomechanics (jump landing) among individuals with and without a concussion history. The main question it aims to answer is if theta burst stimulation to the left dorsolateral prefrontal cortex improves single- and dual-task jump landing reaction time and jump landing biomechanics compared to a control site (vertex) for individuals with and without a concussion history. Participants will be asked to perform a jump landing before and after the experimental (left dorsolateral prefrontal cortex) and control (vertex) theta burst stimulation protocol. The researchers will compare individuals with and without a concussion history to see if the effects differ between groups.
Key facts
- Study ID
- NCT06093295
- Run by
- University of Georgia
- People needed
- 40
- Starts
- 2023-11-03
- Expected to finish
- 2024-05-30
- Last updated by the study team
- 2025-01-09
Who can join
Age: 18 and older, up to 35. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- All participants
- self-report to be physically active at least 90 minutes per week
- aged 18-35 years old
- self-report cleared for sports and physical activity
- Concussion history group
- self-report experiencing a concussion with the National Institute of Health common data element form
- No concussion history group - self-report not experiencing a concussion with the National Institute of Health common data element form
You may not qualify if…
- All Participants
- self-report attention deficit disorder and/or attention deficit hyperactivity disorder
- self-report uncorrected vision problems (not included color blindness)
- self-reported history of neurological disease
- self-reported history of seizures/syncope or family history of epilepsy
- self-reported history of frequent severe headaches or migraine.
- self-reported history of respiratory or heart disease.
- self-reported structural brain lesions (e.g., stroke)
- self-reported increased intracranial pressure, such as after infarctions or trauma.
- self-reported currently using antidepressants, neuroleptic medication, medication that lowers seizure threshold, or any other medication that would interfere with testing.
- self-reported currently experiencing a high fever (day of testing; >102.9 degrees)
- self-reported currently undergoing immunosuppressive therapy
- pregnancy
- metal anywhere in the head (except the mouth).
- any electronic implant, such as a cardiac pacemakers, cochlear implant, or deep brain stimulator.
- any implanted medication pump or intracardiac lines.
- self-report not being cleared for sport/physical activity by a medical practitioner (i.e., must be cleared by a medical practitioner to participate if the participant had previous traumatic musculoskeletal injury)
- students working directly in the PI's lab (concussion laboratory, biomechanics laboratory)
- NCAA athletes
- Concussion history group
- ≥13 symptom severity on the Sport Concussion Assessment Tool (22 total symptoms are graded on a scale of 0-6. Any symptom with a score >0 [1-6], is summed to get symptom severity).
Where it is running
- University of Georgia — Athens, Georgia, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.