Malnutrition Screening and Dietary Intervention to Improve Nutrition Outcomes in Patients With Unresectable Pancreatic Cancer
Running, not enrolling · Not applicable
Conditions studied: Stage III Pancreatic Cancer, Pancreatic Adenocarcinoma Non-resectable
In brief
This clinical trial compares the effect of malnutrition screening and dietary intervention to standard nutrition care on patients with pancreatic cancer that cannot be removed by surgery (unresectable). Fewer than 20% of patients diagnosed with unresectable pancreatic cancer do not survive one year after diagnosis so treatment often focuses on improving quality of life. Many patients experience increasing pain, nausea, vomiting, loss of appetite, weight loss and weakness. Behavioral interventions use techniques to help patients change the way they react to environmental triggers that may cause a negative reaction. Screening for inadequate nutrition (malnutrition) and providing weekly nutritional support may be effective methods to improve nutritional status and improve overall quality of life for patients with unresectable pancreatic cancer.
Key facts
- Study ID
- NCT06090916
- Run by
- Jonsson Comprehensive Cancer Center
- People needed
- 100
- Starts
- 2023-01-17
- Expected to finish
- 2028-03-31
- Last updated by the study team
- 2026-05-26
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Unresectable pancreatic adenocarcinoma, receiving either 1) no chemotherapy, 2) 1st cycle of chemotherapy, or 3) greater than 1 cycle of chemotherapy if the patient's prognosis is greater than 6 months as determined by oncology collaborators
- Life expectancy of greater than 3 months and a Karnofsky performance score of 60 or more
- Adults >= 18 years old male or female
You may not qualify if…
- Ascites requiring paracentesis for symptom improvement
- Aspartate aminotransferase (AST) or alanine aminotransferase (ALT) values greater than 5 times the upper limit of normal
- Creatinine value greater than 2.0 for men and 1.5 for women
- Uncontrolled pain
- Uncontrolled nausea and vomiting
Where it is running
- UCLA / Jonsson Comprehensive Cancer Center — Los Angeles, California, United States
Full record on ClinicalTrials.gov
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