Real-World Evidence on the Cardiovascular Safety of CONTRAVE® in the United States (U.S.)

Completed

Conditions studied: Obesity

In brief

The fixed-dose combination of naltrexone 8mg and bupropion 90mg extended-release oral tablet is marketed under the trade name CONTRAVE® in the U.S. In this protocol, the investigators propose to generate real-world evidence (RWE) from electronic health records (EHR) and linked claims data to assess the cardiovascular safety of CONTRAVE® and all combined use of naltrexone and bupropion (NB) in usual clinical practice.

Key facts

Study ID
NCT06090461
Run by
Currax Pharmaceuticals
People needed
31889
Starts
2014-09-01
Expected to finish
2022-12-01
Last updated by the study team
2025-06-25

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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