Investigation of the Effects of Sleep Fragmentation on Itch and Pain Sensitivity
Recruiting now · Not applicable
Conditions studied: Histamine, Cowhage, Sleep Fragmentation
In brief
In This experiment, the investigators would like to test following hypotheses regarding the influence of sleep fragmentation on itch: * To investigate similarity and differences between itch and pain by comparing the effect of sleep deprivation in them. * To evaluate the inflammatory state induced by sleep fragmentation via the analysis of C-reactive protein (CRP) levels from blood samples. * To correlate the anxiety and depression scores (evaluated through questionnaires) with itch and pain sensitivity and evaluate how they are affected by sleep fragmentation.
Key facts
- Study ID
- NCT06081946
- Run by
- Aalborg University
- People needed
- 30
- Starts
- 2023-12-15
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2024-11-22
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Healthy men and women
- 18-60 years
- Speak and understand English
- Access to a smartphone during the experimental nights
You may not qualify if…
- Pregnancy or lactation
- Drug addiction defined as any use of cannabis, opioids, or other drugs
- Previous or current history of neurological, dermatological, immunological musculoskeletal, cardiac disorder or mental illnesses (psychiatric diagnosis) that may affect the results (e.g., neuropathy, muscular pain in the upper extremities, anxiety, depression, schizophrenia etc.)
- Moles, wounds, scars, or tattoos in the area to be treated or tested
- Current use of medications that may affect the trial such as antihistamines and pain killers.
- Skin diseases
- Consumption of alcohol or painkillers 24 hours before the study days and between these
- Acute or chronic pain and itch
- Participation in other trials within 1 week of study entry (4 weeks in the case of pharmaceutical studies)
- Lack of ability to cooperate
Where it is running
- Aalborg University — Aalborg, Denmark (enrolling)
Full record on ClinicalTrials.gov
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