Pulmonary Artery Catheterization and Carvedilol Early Initiation in Cardiogenic SHOCK Due to HFrEF

Recruiting now · Not applicable

Conditions studied: Heart Failure With Reduced Ejection Fraction, Cardiogenic Shock

In brief

This study aims to compare the impact of hemodynamic monitoring using pulmonary artery catheter (PAC) on survival and inotropic agent reduction in patients with cardiogenic shock caused by heart failure with reduced ejection fraction (HFrEF). The investigators also intend to compare the difference in long-term survival rates among patients who have recovered from cardiogenic shock due to HFrEF, based on the timing of initiation of beta-blocker treatment.

Key facts

Study ID: NCT06078436
Run by: Min-Seok Kim
People needed: 160
Starts: 2024-01-01
Expected to finish: 2028-03-01
Last updated by the study team: 2024-01-05

Who can join

Age: 19 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Adults age 19 and above ( no age limit for elderly )
Patients with cardiogenic shock requiring intensive care monitoring in ICU
Patients eligible for oral medication administration
Patients who have provided research participation consent through a written informed consent form

You may not qualify if…

Unwilling or unable to obtain informed consent by the participant or substitute decision maker
Patients with mechanical circulatory support at the time of screening
Patients with acute coronary syndrome
Patients with severe valvular heart disease requiring emergent percutaneous procedures or surgery
Known hypersensitivity to beta-blockers
Patients with a history of bronchospasm or asthma
Patients with bradycardia or second or third-degree atrioventricular block
Patients with sick sinus syndrome, including sinoatrial block
Patients with untreated pheochromocytoma
Patients currently undergoing de-sensitization therapy
Patients who are currently pregnant, postpartum period within 30 days or breast-feeding

Where it is running

Asan Medical Center — Seoul, South Korea (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.