Cognitive Remediation of Working Memory Post Head Trauma
Recruiting now · Not applicable
Conditions studied: Head Trauma
In brief
Patients with working memory deficits due to a moderate to severe head injury will undergo a 5 month protocol including cognitive remediation with numerous exercises, transcranial direct current stimulation (tDCS), and therapeutic education.
Key facts
- Study ID
- NCT06077695
- Run by
- University Hospital, Toulouse
- People needed
- 9
- Starts
- 2025-11-06
- Expected to finish
- 2027-07-06
- Last updated by the study team
- 2026-08-07
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Moderate or severe head trauma, defined by an initial Glasgow score ≤ 12/15, duration of post-traumatic amnesia superior to 24 hours and/or the presence of abnormalities on brain imaging,
- Moderate or severe head trauma occurring within a period greater than or equal to 3 months,
- Working memory complaints assessed by the Working Memory Questionnaire,
- Patients with a working memory disorder in at least one of the following tests: Digit Memory subtest WAIS-IV (standard deviation ≤ -2) , PASAT (percentile ≤ 10), Brown-Peterson (standard deviation ≤ -2).
You may not qualify if…
- Presence of aphasia, apraxia or severe neglect demonstrated by standardized neuropsychological tests during the inclusion visit: language - oral naming of BECS-GRECO images, ideational praxis and ideomotor , neglect - bell test,
- Insufficient visual or auditory abilities and oral and written expression to carry out neuropsychological tests,
- Severe depression assessed by the Beck Depression Inventory (BDI)
- Chronic alcoholic poisoning, drug addiction,
- Progressive general illness,
- Progressive psychiatric or neurological condition leading to cognitive impairment,
- Hospitalization for a neurological pathology since the acute phase of the qualifying event,
- Patient requiring surgery during study participation.
- Pregnant or breastfeeding women
Where it is running
- UH Toulouse — Toulouse, France (enrolling)
Full record on ClinicalTrials.gov
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