Immersive Healing: The Therapeutic Potential of Virtual Reality

Recruiting now · Not applicable

Conditions studied: Phantom Limb Pain (PLP)

In brief

Phantom limb pain (PLP) is a significant and pervasive issue among upper limb amputees, severely impacting their quality of life. The literature delineating prevalence of upper versus lower limb amputations is limited, but the prevalence of total amputations in the United States is estimated to reach 3 million individuals by 2050, with approximately 185,000 new cases annually. PLP affects 60-68% of these patients, leading to heightened levels of anxiety, depression, and reduced overall well-being.

Key facts

Study ID

NCT06077227

Run by

Wake Forest University Health Sciences

People needed

20

Starts

2023-12-21

Expected to finish

2026-10-01

Last updated by the study team

2026-07-31

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• History of major limb amputation
• Age > 18 years old
• Presence of phantom limb pain or negative phantom sensation(s)

You may not qualify if…

• Active mental illness, neurological disease, or cognitive impairment that would interfere with survey completion
• Those without phantom limb pain or negative phantom limb sensations
• Non-English speaking

Where it is running

• OrthoCarolina Hand Center — Charlotte, North Carolina, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.