Sex Difference of Coronary Microvascular Dysfunction in Patients With Non-obstructive Coronary Artery Disease

Recruiting now

Conditions studied: Microvascular Angina

In brief

Sex difference of coronary microvascular dysfunction evaluated by coronary flow reserve will be assessed in patients with non-obstructive coronary artery disease

Key facts

Study ID

NCT06076551

Run by

Korea University Anam Hospital

People needed

300

Starts

2018-02-01

Expected to finish

2025-12-31

Last updated by the study team

2025-03-26

Who can join

Age: 20 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Typical/atypical chest pain or ischemic symptoms including dyspnea
• No significant coronary artery stenosis (<50% stenosis) in coronary angiography or computed tomography

You may not qualify if…

• ≥ Moderate valvular heart disease
• Congenital heart disease
• Chronic renal failure (estimated glomerular filtration rate <30 ml/min/1.73m2) or end-stage renal failure undergoing hemodialysis or peritoneal dialysis
• Asthma, chronic obstructive pulmonary disease and primary pulmonary hypertension
• Receiving anticancer drugs
• Vasculitis associated with autoimmune diseases
• Atrioventricular block with more than second degrees, symptomatic bradycardia, cryo-node failure syndrome, Wolff-Parkinson-White (WPW) patients

Where it is running

• Korea University Anam Hospital — Seoul, South Korea (enrolling)

Full record on ClinicalTrials.gov

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