Emergency Resuscitative Endovascular Balloon Occlusion of the Aorta in Out of Hospital Cardiac Arrest

Recruiting now · Not applicable

Conditions studied: Out-Of-Hospital Cardiac Arrest, Cardiac Arrest, Cardiac Arrhythmia, Ventricular Fibrillation, Ventricular Arrythmia, Pulseless Electrical Activity

In brief

This study will assess the feasibility of performing pre-hospital resuscitative endovascular balloon occlusion of the aorta (REBOA) as an adjunct to conventional Advanced Life Support (ALS) in patients suffering from non-traumatic out of hospital cardiac arrest (OHCA). As well as providing valuable insights into the technical feasibility of performing this procedure as part of a resuscitation attempt, the study will also document the beneficial physiological effects of REBOA in this group of patients.

Key facts

Study ID: NCT06071910
Run by: Queen Mary University of London
People needed: 40
Starts: 2024-06-04
Expected to finish: 2026-12-31
Last updated by the study team: 2026-03-02

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Non-Traumatic OHCA in patients within the East of England area AND with a East Anglian Air Ambulance (EAAA) REBOA team in attendance
Patients below or equal to 80yrs of age and above or equal to 18yrs of age, according to available information/estimate at scene
No flow <10 mins from data available (i.e. total period in OHCA with no CPR)
In cardiac arrest (with no sustained ROSC) on arrival of the EAAA REBOA team

You may not qualify if…

Patients aged less than 18 or above 80 years
Known terminal illness
Multiple severe co-morbidities
Traumatic Cardiac Arrest (TCA)
Inability to deploy mechanical CPR (e.g. LUCAS Device)
Pregnancy, obvious or suspected

Where it is running

East Anglian Air Ambulance — Norwich, United Kingdom (enrolling)

Full record on ClinicalTrials.gov

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