The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)

Recruiting now · Phase 1

Conditions studied: Alcohol Use Disorder (AUD), Alcohol-Related Disorders, Alcohol Use

In brief

This proposed study is a double-blind, randomized, placebo-controlled, parallel-group, laboratory study to determine the effects of DMT, plus psychotherapy, on Alcohol Use Disorder.

Key facts

Study ID

NCT06070649

Run by

Yale University

People needed

63

Starts

2025-08-04

Expected to finish

2026-08-01

Last updated by the study team

2026-04-28

Who can join

Age: 21 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnostic and Statistical Manual of Mental Disorders-5th edition (DSM-5) diagnosis of Alcohol Use Disorder
• Medically healthy
• Ability to provide consent

You may not qualify if…

• Unstable medical conditions

Where it is running

• Connecticut Mental Health Center — New Haven, Connecticut, United States (enrolling)

Full record on ClinicalTrials.gov

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