Greater Occipital Nerve Blockade in Veterans With Post-concussion Headache: Sub-study 1
Recruiting now · Phase 1
Conditions studied: Post-Traumatic Headache
In brief
The acute and subacute sensations that occur on the scalp with injection of different concentrations of bupivacaine for grater occipital nerve blockade will be compared. Each Veteran participant will be randomized to receive three different concentrations, which will be injected one week apart each.
Key facts
- Study ID
- NCT06069791
- Run by
- Yale University
- People needed
- 12
- Starts
- 2024-01-26
- Expected to finish
- 2026-12-31
- Last updated by the study team
- 2026-01-29
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- United States Military Veterans within VA Connecticut Healthcare System
- Chronic post-traumatic headache per ICHD-3 criteria (i.e., headaches are continuing to occur three months after the head injury)
- At least two headache days per week
- MRI brain scan completed within the past 3 months if chronic PTH for less than one year, within the past year if chronic PTH for less than 5 years, and within 5 years if chronic PTH for more than 10 years
- Review of MRI and the medical record does not reveal another source for headache
You may not qualify if…
- Skull defect
- Other contraindication to bupivacaine
- Allergy or adverse reaction (e.g., rash, cardiac effects) to amide anesthetics, such as lidocaine
- Instruction from clinician to avoid amide anesthetics, such as lidocaine
- Pregnant or lack of adequate birth control
Where it is running
- VA Connecticut Healthcare System — West Haven, Connecticut, United States (enrolling)
Full record on ClinicalTrials.gov
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