Open-Label Extension of EDG-5506 in Participants With Becker Muscular Dystrophy

Enrolling by invitation · Phase 2

Conditions studied: Becker Muscular Dystrophy

In brief

EDG-5506-203 MESA is an open-label extension study to assess the long-term effect of sevasemten (EDG-5506) on safety, biomarkers, and functional measures in adults and adolescents with Becker muscular dystrophy

Key facts

Study ID

NCT06066580

Run by

Edgewise Therapeutics, Inc.

People needed

260

Starts

2023-11-02

Expected to finish

2031-02-01

Last updated by the study team

2026-07-31

Who can join

Age: any. Sex: male. Healthy volunteers: not accepted.

Where it is running

• Arkansas Children's Hospital — Little Rock, Arkansas, United States
• UC San Diego — La Jolla, California, United States
• UCLA Medical Center — Los Angeles, California, United States
• UC Irvine Medical Center — Orange, California, United States
• Stanford Neuroscience Health Center — Palo Alto, California, United States
• UC Davis Medical Center — Sacramento, California, United States
• UC Denver — Aurora, Colorado, United States
• University of Florida — Gainesville, Florida, United States
• Rare Disease Research — Atlanta, Georgia, United States
• Northwestern University — Chicago, Illinois, United States
• Indiana University School of Medicine — Indianapolis, Indiana, United States
• University of Iowa — Iowa City, Iowa, United States
• University of Kansas Medical Center — Kansas City, Kansas, United States
• Kennedy Krieger Institute — Baltimore, Maryland, United States
• University of Massachusetts Memorial Medical Center — Worcester, Massachusetts, United States
• Washington University School of Medicine — St Louis, Missouri, United States
• University of Rochester Medical Center — Rochester, New York, United States
• Rare Disease Research, LLC NC — Hillsborough, North Carolina, United States
• University of Cincinnati Gardner Neuroscience Institute — Cincinnati, Ohio, United States
• Nationwide Children's Hospital — Columbus, Ohio, United States
• University of Pennsylvania — Philadelphia, Pennsylvania, United States
• National Neuromuscular Research Institute — Austin, Texas, United States
• Neurology Rare Disease Center — Denton, Texas, United States
• Virginia Commonwealth University Health — Richmond, Virginia, United States
• University Hospital Gent — Ghent, Belgium

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.