Spatial-Motor Stroke-Rehab Study
Recruiting now · Not applicable · Has a placebo group
Conditions studied: Spatial Neglect, Stroke
In brief
The purpose of this study is to understand how prism adaptation training with and without electrical stimulation changes visuospatial behavior, motor system neurophysiology, and walking dysfunction.
Key facts
- Study ID
- NCT06053320
- Run by
- Emory University
- People needed
- 65
- Starts
- 2023-04-11
- Expected to finish
- 2026-09-01
- Last updated by the study team
- 2026-05-20
Who can join
Age: 18 and older, up to 90. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Young Adults Able Bodied (YAB) Individuals
- 18-30 years
- Able-Bodied (healthy without any physical disability or neurological disorder)
- Older Adults Able-Bodied Individuals (OAB)
- 45-90 years
- Able-Bodied (healthy without any physical disability or neurological disorder)
- Individuals with right hemisphere stroke (40-90 years)
- >3 months following stroke.
- Presence of Aiming SN
- Ability to walk >10m with or without assistive devices.
- Unilateral left-sided hemiparesis with gross arm strength of ≤ grade 4/5 on the Medical Research Council Scale
- Ability to follow 3-stage commands and provide informed consent.
You may not qualify if…
- Young Adults Able-Bodied (YAB) Individuals and Older Adults Able-Bodied Individuals (OAB)
- History or evidence of orthopedic or physical disability
- History or evidence of neurological pathology
- Pregnancy (female)
- Uncontrolled hypertension
- Cardiac pacemaker or other implanted electronic system
- Presence of skin conditions preventing the electrical stimulation setup
- Impaired sensation in the left upper limb.
- Bruises or cuts at the stimulation electrode placement site
- Concurrent enrollment in rehabilitation or another investigational study.
- History or evidence of orthopedic or physical disability interfering with study procedures
- History or evidence of neurological pathology or disorder
- Severe uncontrolled medical problems (e.g., hypertension, cardiovascular disease, rheumatoid arthritis, active cancer or renal disease, epilepsy) that may interfere with study procedures
- Contraindications to TMS, such as metal implants, medications that can increase cortical excitability, and unexplained dizziness in the past 6 months
- Individuals with right hemisphere stroke (40-90 years)
- History or brainstem strokes
- Cerebellar disorders
- Impaired sensation in the left upper limb.
- History of other neurological disorders
- Uncontrolled hypertension
- Cardiac pacemaker or other implanted electronic system
- Pregnancy (female)
- Presence of skin condition
- Bruises at the electrode placement site
- Severe uncontrolled medical problems (e.g., hypertension, cardiovascular disease, rheumatoid arthritis, active cancer or renal disease, epilepsy) or other medical conditions that can interfere with study procedures
Where it is running
- Emory Rehabilitation Hospital — Atlanta, Georgia, United States (enrolling)
- Emory University Hospital (EUH) — Atlanta, Georgia, United States (enrolling)
- Executive Park — Atlanta, Georgia, United States (enrolling)
Full record on ClinicalTrials.gov
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